TB-Profiler result

Run: SRR7504771
Summary

Run ID: SRR7504771

Sample name:

Date: 2025-03-07T21:42:30.989344

Number of reads: 101804802

Percentage reads mapped: 99.91

Median coverage: 403.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
thyX 3067746 p.Val67Ala missense_variant 0.22 para-aminosalicylic_acid Uncertain significance
whiB7 3569039 c.-360T>C upstream_gene_variant 0.28 amikacin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
embA 4244481 p.Leu417Phe missense_variant 0.12 ethambutol Uncertain significance