TB-Profiler result

Run: SRR638895
Summary

Run ID: SRR638895

Sample name:

Date: 2025-03-06T12:34:44.300432

Number of reads: 8604739

Percentage reads mapped: 99.03

Median coverage: 118.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 1054 p.Ala352Pro missense_variant 0.24 isoniazid Uncertain significance
fgd1 491014 p.Thr78Pro missense_variant 0.33 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
mshA 575308 c.-40A>G upstream_gene_variant 0.29 ethionamide Uncertain significance
isoniazid Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 0.99 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rpoA 3878580 c.-73A>C upstream_gene_variant 0.39 rifampicin Uncertain significance